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Buy Tadalafil
Cialis is a registered trademark in US of Eli Lilly and Company.
If you are buying Tadalafil for the first time, start with a small amount to make sure that drug works for you and then order more later.
If you have been taking this medicine for a while and will continue to take it regularly, buy as much Tadalafil as you can at once.
Our online pharmacy offer discounted prices when you buy Tadalafil in large quantities. Plus, you won't have to worry about refills for a while.
Tadalafil
Tadalafil contains the active ingredient tadalafil, which is a medicine used in the treatment of erectile dysfunction. Tadalafil is called a phosphodiesterase type 5 inhibitor, and works by preventing the action of a chemical in the body called phosphodiesterase type 5.
An erection is produced via a complex chain of events, involving signals from the nervous system and the release of chemical messengers within the tissues of the penis. One of these chemical messengers is called cyclic GMP.
Cyclic GMP causes the blood vessels in the penis to widen by relaxing a thin layer of muscle found in the blood vessel walls. This allows more blood to enter the penis, which ultimately results in the penis becoming rigid and erect.
Cyclic GMP is normally broken down by another chemical in the body called phosphodiesterase type 5. Tadalafil works by preventing the action of phosphodiesterase type 5, thus stopping the breakdown of cyclic GMP. This means that the blood vessels are kept dilated for longer, improving blood flow to the penis and maintaining an erection.
As tadalafil enhances the actions of the chemical messengers responsible for producing an erection, it will only work once these messengers are present. This means that sexual stimulation is required for it to produce and maintain an erection. The dose should be taken at least 30 minutes before intended intercourse, and it may produce an erection in response to sexual stimulation for up to 36 hours after taking the dose.
Dosage
Adult Males
Doses range from 5 mg to 20 mg, depending on the drug's effect.
The recommended starting dose is 10 mg.
Take Tadalafil only before sexual activity. The manufacturer recommends a maximum of one dose per day.
If you're taking certain drugs that affect the liver, such as ritonavir (Norvir) or ketoconazole (Nizoral), the maximum recommended dose is 10 mg no more than once every 3 days.
If you have moderate kidney impairment, the recommended starting dose is 5 mg once a day, up to a maximum of 10 milligrams once every 2 days.
If you have severe kidney impairment or need dialysis, the maximum recommended dose is 5 mg once a day.
No dosage adjustment is required if you have mild kidney problems.
If you have mild or moderate liver impairment, your total daily dose should not exceed 10 mg once a day.
If your liver is severely impaired, you will not be able to use Tadalafil.
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