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Crestor



Generic Name: Rosuvastatin


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Buy Crestor

If you are buying Crestor for the first time, start with a small amount to make sure that drug works for you and then order more later. If you have been taking this medicine for a while and will continue to take it regularly, buy as much Crestor as you can at once. Our online pharmacy offer discounted prices when you buy Crestor in large quantities. Plus, you won't have to worry about refills for a while.

Crestor

Crestor contains the active ingredient rosuvastatin calcium, which is a type of medicine called a statin. It works by reducing the production of cholesterol by the liver.

For the sake of simplicity, there are two sorts of cholesterol; a 'bad' sort called low density lipoprotein (LDL) and a 'good' sort called high density lipoprotein (HDL). LDL is deposited in the arteries and increases the risk of heart disease by clogging and narrowing the arteries, while HDL actually protects the arteries against this.

Crestor decreases the production of LDL cholesterol by blocking the action of the enzyme in the liver that is responsible for its production. This decreases the amount of cholesterol in the liver cells, which causes them to take up LDL cholesterol from the blood. The decreased cholesterol production and increased removal of LDL cholesterol from the blood ultimately results in lowered blood cholesterol levels.

Crestor also causes a small decrease in the production of other 'bad fats' in the blood called triglycerides, and a small increase in the level of HDL cholesterol. This results in lowered levels of 'bad fats' and raised levels of 'good fats'.

Statins have an important role in the prevention of coronary heart disease. They reduce the risk of excess cholesterol being deposited in the major blood vessels of the heart. Any blockage in the blood vessels limits the amount of blood and therefore oxygen being carried to the heart muscle. This can cause chest pain and in severe cases can result in a heart attack.

Rosuvastatin is used to lower cholesterol in people who have high levels either due to genetics or as a result of diet and lifestyle. This helps to reduce the risk of atherosclerosis, angina and heart attacks.

It is important to continue to follow a cholesterol-lowering diet and exercise regime while taking Crestor. Discuss this with your doctor.

Dosage

Hypercholesterolemia and mixed dyslipidemia: Starting dose: 10 mg once daily; 5 mg once daily if risk factors for myopathy; 20 mg once daily if low-density lipoprotein cholesterol is >190 mg/dL. Maintenance dose: 5 mg to 40 mg once daily.
Homozygous familial hypercholesterolemia: Starting dose: 20 mg once daily. Maintenance dose: 20 mg to 40 mg once daily.
Patients taking cyclosporine: Starting and maintenance dose: 5 mg once daily.
Patients taking concomitant gemfibrozil: Maximum dose: 10 mg once daily.
Patients with mild to moderate renal insufficiency: No dosage modification needed.
Patients with severe renal impairment not on hemodialysisc: Starting dose: 5 mg once daily. Maintenance dose: 5 mg to 10 mg once daily.

 
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