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Buy Coumadin
If you are buying Coumadin for the first time, start with a small amount to make sure that Coumadin works for you and then order more later.
If you have been taking Coumadin for a while and will continue to take it regularly, buy as much Coumadin as you can at once.
Our online drug store offer discounted prices when you buy Coumadin in large quantities.
Plus, you won't have to worry about refills for a while.
Coumadin
Coumadin contains the active ingredient warfarin sodium, which is a type of medicine called an oral anticoagulant. It is used to stop blood clots forming within the blood vessels.
Blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. The clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. Clotting factors are proteins that are produced by the liver. Vitamin K is essential for their production. The activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. Fibrin binds the platelets together, forming a blood clot. This is the body’s natural way of repairing itself.
Sometimes, however, a blood clot can form abnormally within the blood vessels. This is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. The clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. This is known as a thromboembolism.
Some people have an increased tendency for blood clots to form within the blood vessels. This is usually due to a disturbance in the blood flow within the blood vessels. For example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. Slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). These clots can break off and travel to the lungs (pulmonary embolism). A type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. Heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. Clots in the heart can detach and travel to the brain, causing a stroke. Coumadin is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these.
Warfarin works by preventing the vitamin K dependent production of the clotting factors described above. Coumadin prevents the production of these clotting factors by inhibiting the action of vitamin K. Without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur.
Coumadin takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. For this reason, when treating blood clots such as deep vein thrombosis or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with.
Dosage
Older Adults
Low starting and maintenance doses are recommended for older people, as the drug tends to have a greater effect.
Adults
The starting dose of Coumadin tablets for adults is 2 to 5 mg per day.
Individualized daily dosage adjustments are based on the results of tests that determine the amount of time it takes for the blood clotting
process to begin.
A maintenance dose of 2 to 10 mg a day is satisfactory for most people.
The duration of treatment will be determined by your physician.
Children
Although Coumadin has been widely used in children below the age of 18, its safety and effectiveness for this purpose have not been formally established.
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